Rice University logoDr. Rebecca Richards-Kortum
 
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Optical Spectroscopy and Imaging Laboratory
 
 

 

Point-of-Care Diagnostic Tools to Improve Global Cervical Control Programs 

 

Agency: NCI / NIH

Collaborators: Rebecca Richards-Kortum (Rice), Kathleen Schmeler (UTMDACC), Phil Castle (AECOM), Jose Fregnani (Barretos Cancer Hospital)

The goal of this project is to optimize and validate a high resolution microendoscope (HRME) to be used in see and-treat programs to improve specificity without reducing sensitivity. The performance of the HRME for real-time diagnosis of cervical cancer in urban and rural settings will be tested in Brazil. In the UH2 phase, we will demonstrate successful implementation of the HRME in a novel mobile diagnostic and treatment unit for real-time diagnosis and treatment of cervical precancer in screen-positive women in a single visit in order to reduce the number of women lost to follow-up. In the UH3 phase, we will carry out a study involving over 12,000 women to validate that the HRME has improved diagnostic sensitivity and specificity compared to VIA and colposcopy for combined diagnosis and treatment in a single visit. Our project will validate the use of HRME as a real-time, in vivo diagnostic tool that can be applied in a variety of scenarios as an alternative to the traditional diagnostic methods of colposcopy and biopsy, which are impractical in many LMICs. 

 RRK HRME 

 Cells 

 RRK Brazil   

  Click HERE to watch the VIDEO 


 


 

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