Rice University logoDr. Rebecca Richards-Kortum
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Optical Spectroscopy and Imaging Laboratory


Point-of-Care Diagnostic Tools to Improve Global Cervical Control Programs 


Agency: NCI / NIH

Collaborators: Rebecca Richards-Kortum (Rice), Kathleen Schmeler (UTMDACC), Phil Castle (AECOM), Jose Fregnani (Barretos Cancer Hospital)

The goal of this project is to optimize and validate a high resolution microendoscope (HRME) to be used in see and-treat programs to improve specificity without reducing sensitivity. The performance of the HRME for real-time diagnosis of cervical cancer in urban and rural settings will be tested in Brazil. In the UH2 phase, we will demonstrate successful implementation of the HRME in a novel mobile diagnostic and treatment unit for real-time diagnosis and treatment of cervical precancer in screen-positive women in a single visit in order to reduce the number of women lost to follow-up. In the UH3 phase, we will carry out a study involving over 12,000 women to validate that the HRME has improved diagnostic sensitivity and specificity compared to VIA and colposcopy for combined diagnosis and treatment in a single visit. Our project will validate the use of HRME as a real-time, in vivo diagnostic tool that can be applied in a variety of scenarios as an alternative to the traditional diagnostic methods of colposcopy and biopsy, which are impractical in many LMICs. 



 RRK Brazil   

  Click HERE to watch the VIDEO 



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